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Ocular Cicatricial Pemphigoid

OCP 

What is Ocular Cicatricial Pemphigoid (OCP)?

Ocular cicatricial pemphigoid (OCP) is the eye disease affecting patients with mucous membrane pemphigoid (MMP). The most up-to-date term for the condition is ocular mucous membrane pemphigoid (ocular MMP).

OCP is a rare, potentially sight-impairing autoimmune disease affecting the conjunctiva. The conjunctiva is the transparent mucous membrane lining which covers the white of the eye and the undersurface of the eyelids. In OCP the conjunctiva becomes red, inflamed and progressively scarred, leading to inturned eyelashes.

“Ocular” means eye, “cicatricial” means scarring, and “pemphigoid” is an autoimmune blistering disease.

OCP can be isolated to the eye alone (in 18 to 50% of patients with eye disease). More commonly it occurs as part of the whole-body condition called mucous membrane pemphigoid (MMP), which causes painful blistering, inflammation & scarring of the moist surfaces of the body (known as mucous membranes) including the mouth and gums, the lining of the nose, oesophagus (the swallowing tract), larynx (voice box), genitals, rectum, ear, eyes and skin. About 70% of whole-body MMP patients have eye involvement.

The following information is provided as a guide only. Careful assessment and treatment by an eye specialist (ophthalmologist) who has the expert training and experience to accurately determine your diagnosis and best treatment approach is important.

What causes Ocular Cicatricial Pemphigoid (OCP)?

OCP is an autoimmune disease where the body’s immune system is overactive and mistakenly attacks otherwise healthy tissue, causing blistering, inflammation and scarring. Examples of other autoimmune diseases include rheumatoid arthritis and lupus.

Ocular cicatricial pemphigoid can be triggered by drugs or eye drops, or occasionally occurs following other diseases such as Stevens Johnson Syndrome, but in the majority of patients the trigger is not identifiable. The overactive immune system produces antibodies which mistakenly recognize parts of the body as foreign, leading to blistering damage, inflammation and scarring.

OCP is not contagious and not affected by diet or lifestyle.

Who is usually susceptible to OCP?
OCP predominantly affects adults aged 40 – 70, with women affected slightly more often than men. However it can occur in 20-30 year olds, and also in children.
What are the symptoms of Ocular Cicatricial Pemphigoid (OCP)?

The commonest symptoms of OCP are:

 

  • Inturned eyelashes (trichiasis) rubbing the eye ***

 

  • Red, gritty sore or dry eyes with sensitivity to light

 

  • Conjunctivitis (red sticky eye) that keeps returning despite courses of antibiotic eyedrops

 

  • Droopiness and closing of the eyelid

 

*** If you have inturned eyelashes that often need to be pulled out, it is essential to have a careful assessment by an eye consultant who is expert in diagnosing ocular cicatricial pemphigoid, to evaluate the underlying cause of the inturned eyelashes. ***

How will I know if OCP is affecting other parts of my body?
Symptoms of mucous membrane pemphigoid (MMP) affecting other parts of the body including mouth ulcers, bleeding gums, nose bleeds, skin rash or blisters, difficulty swallowing, a hoarse voice, blood in the motions, genital sores and difficulty hearing. It is important to let your OCP specialist know if you are experiencing any of these symptoms.
How is OCP diagnosed?

A small sample of tissue (biopsy) is taken from the eyes and usually also the mouth. These biopsies are evaluated under a fluorescence microscope and tested for antibodies associated with MMP. Whilst biopsies from skin and mouth MMP lesions are less than 10% likely to give false negative results, unfortunately biopsies from the eye can give a false negative result in 30-50% of cases. So a positive result from the eye confirms the diagnosis, but a negative result from the eye does not necessarily mean that the diagnosis is not MMP. In a proportion of patients with negative biopsy results, treatment with immunosuppressive therapy (which suppresses an overactive immune system) in a similar manner to patients with positive biopsy results, may be necessary.

A blood test may also be used to detect the antibodies in the circulation, but they are detectable in less than 30% of ocular MMP patients.

If it is likely that you will require immunosuppressive medication (which suppresses an overactive immune system), Ms Saw will request that you have baseline pre-treatment blood tests (including a full blood count, electrolytes & renal function, liver function tests) to establish if there are any pre-treatment abnormalities which require investigation or treatment, or which may alter her decision regarding which immunosuppressive medication would be best for your situation. These blood tests are usually done at the time that the biopsies are taken.

Once a diagnosis of OCP is made, you may be referred to a Dermatologist, an Oral Medicine specialist and/or an Ear, Nose & Throat (ENT) specialist, depending on your symptoms. Multi-disciplinary care is essential for successful management of OCP/ MMP.

How is OCP treated?

Because it is an autoimmune condition, treatment of OCP requires strong oral medication as tablets or injections, called immunosuppressive therapy (which suppresses the overactive immune system). This treatment may be required for several months, years or indefinitely. Regular blood tests are required to check for unwanted effects of treatment in the first weeks to months of treatment. Immunosuppressive medication used in OCP include mycophenolate, cyclophosphamide, methotrexate, and dapsone. Limited courses of oral prednisolone (steroid) may also be used.

 

Eye drops cannot alter the progressive nature of the condition – only immunosuppressive medication can do this – but steroid drops may be used for short periods to reduce inflammation. Long term use of steroid eye drops can lead to eye infections, glaucoma and cataract so they are not used long term in OCP.

 

Dry eye is common in OCP, due to both (a) scarring and (b) Meibomian gland blockage. Lubricating eye drops/gel/ointment to maintain moisture on the eye, are essential to treat the dry eye.

 

Blepharitis and Meibomian gland dysfunction is common in OCP, and worsens dry eye and eye inflammation.

  • Daily hot compresses with eyelid massage are essential to express “oily tears” from blocked Meibomian glands, to treat dry eye in OCP.
  • Courses of oral Doxycycline or Lymecycline help to reduce inflammation, unblock Meibomian glands and improve tear film quality.
  • Taking omega 3 fish oil supplements has been shown in some studies to improve Meibomian gland function and dry eye.

What can I do?

  • Hot eyelid compresses and massage to express “oily tears” to the surface of your eyes once every day, as part of your daily hygiene routine, will make your eyelids and eyes as healthy as possible.
  • Keep your eyes moist with lubricating drops, gel or ointment – avoid letting dryness cause further damage to the eye.
  • Use your eye drops and take the immunosuppressive medication as instructed by your specialist
  • If any medication makes you feel very unwell, stop it and contact your OCP specialist.
  • If eyelashes are rubbing your eyes, either have them removed by a local optometrist or A&E unit, or enlist the help of a relative or friend using tweezers & magnifying glass. Trying to do it yourself can be difficult. Eyelashes rubbing the eyes can cause an ulcer on the cornea that then gets infected and leads to irreversible sight loss.
  • Stop smoking and reduce alcohol intake to recommended limits

What is the long term disease course in OCP?
In a few patients, the condition can go into remission for 1 year or more and the immunosuppressive medication can be stopped. However the majority of MMP patients continue on oral immunosuppressive medication for life.
Will the immunosuppressive treatment make me feel unwell?
All medications potentially have side effects. If the Ocular Cicatricial Pemphigoid disease itself is making you unwell, immunosuppressive medication is prescribed to relieve this. Most people tolerate immunosuppressive medication well. If you are having side effects from the medication then the dose of the medication could be reduced, or switched to a different medication, in order to find the medication which controls your OCP with minimum side effects.
Is there any treatment which can put the disease into remission?
The only medication which has been reported to put Ocular Cicatricial Pemphigoid into remission for more than 1 year is cyclophosphamide, which is effective but can cause side effects. 
Can I go blind?
Unfortunately some patients can permanently lose their eyesight due to OCP causing permanent scarring of the cornea, the clear front window of the eye, as a consequence of severe dryness, corneal infection or damage to limbal stem cells.

 

What research is currently being carried out in OCP?

Ms Saw is currently involved in planning several research projects involving OCP:

 

  • A laboratory research grant investigating inflammatory dendritic cell pathways in an in vitro model.

 

  • A randomized clinical trial of Rituximab in treatment-recalcitrant OCP.

 

If you would like to receive more information about, or would like to become involved in any of the research projects we would be delighted to hear from you.

 

 

 

 

Useful links:

 

PEM Friends (for people in the UK who suffer from Pemphigus or Pemphigoid) http://pemfriends.co.uk

The International Pemphigus and Pemphigoid Foundation http://www.pemphigus.org

The British Association of Dermatologists http://www.bad.org.uk

 

Valerie Saw has treated hundreds of patients with OCP and is one of the most experienced UK experts in Ocular Cicatricial Pemphigoid.

 

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  • Ms Saw is an outstanding surgeon. Very clear information and individual attention as I had long standing conjunctivitis and blepharitis as well as myopia. Felt fully prepared for the surgery and extremely confident in her skill. Delighted to wholeheartedly recommend both the procedure and Ms Saw. Can’t believe I didn’t have this done years ago!

    Emma Hawkes

  • I received the highest level of professional care from Valerie Saw and her team. I have a pre-existing condition, (Blepharitis) so was anxious about surgery. However, not only has Miss Saw corrected my vision, she has also greatly improved the Blepharitis symptoms with medication, which previous ophthalmologist, GP’s and opticians had not diagnosed/treated adequately. The surgery was quick, pain free and extremely professional. Thank you!

    Andrea Rees

  • From start to finish I felt supported, informed, safe and unpressured. Any concerns were dealt with immediately and I was re-assured at all times. Follow up post op is excellent and more than I had ever expected. Ms Valerie Saw was amazing, so calm, knowledgeable and professional. Moorfields exceeded my expectations and I recommend them to all considering laser surgery. It’s worth spending the extra to know you will have the best.

    Carla Finlayson

  • I feel I have had life changing eye surgery. No more contacts or glasses. Surgery was painless, a little discomfort for a few weeks after but all good now. I have been delighted with my experience and would recommend Ms Valerie Saw.

    Linda Turner

  • I am thrilled with the results. I researched and contacted a number of London based clinics and surgeons and after contacting Ms Saw’s office I was really impressed with the professional and personalised service that her team offered me. When I met with Ms Saw's office the professional and personalised service continued. I am very active and I hold a PPL and we agreed that LASEK was a better choice for me. During the surgery I was grateful that Ms Saw explained what she was doing at each and every step of the very short procedure. During the follow up and aftercare I found Ms Saw and her team to be easily available to answer any questions. My recovery was very fast, aided by the aftercare, and my PPL Medical certificate was re-issued by a CAA Medical Examiner after 3 months instead of the anticipated 12. I am 100% satisfied with my treatment would recommend Ms Saw to anyone considering laser eye surgery.

    Alexander Collis

  • I had absolutely no idea of what to expect when I discovered cataracts in my eyes. And I was living abroad. On my first visit, during my initial consultation Valerie explained in very simple but concise terms what to expect and was able to put my mind at ease. She also fully outlined what type of resulting vision to expect including all the main side effects. I came back to London 3 months later and we were able to operate on both eyes, and I left London a week later, fully armed with instructions and eye drops. Due to being abroad I called once just to discuss over the phone how I felt my vision was and to ensure that I was on track. Once again even from afar Valerie was spot on with advice and suggestions. Six months on and I have had my follow up visit. My eye-sight is perfect, the side effects are minimal. I would highly recommend Valerie Saw to anyone considering eye surgery; you can be certain of being in good, professional hands with optimum results.

    Bola Awoyinka

  • Ms Valerie Saw is a friendly and very professional eye surgeon. She is very thorough during the examination. Valerie immediately put me at ease providing just the right amount of information to enable me to make the right decision about having laser eye surgery (after over 45 years of wearing glasses for astigmatism and myopia the idea was a bit scary!) During the surgery when I was quite nervous Valerie was reassuring, efficient and kept me fully informed. After surgery I received complete care and attention. Valerie made sure I understood exactly what I needed to do to take the best care of my eyes. I now have great vision with no glasses at all, even reading a computer screen all day.

    Chris Stott

  • Well taken care of. Surgery went very well and aftercare excellent. I have 20/20 vision, the best thing I have ever spent my money on. Would recommend LASIK eye surgery.

    Pasqualina Rasile

  • "Calm and clear. I was particularly grateful for being able to contact Valerie both pre and post-surgery with questions. The teams both in Valerie’s practice and at Moorfields were friendly, reassuring and approachable. Thank you for taking such good care of my sight!"

    O. Robinson

  • When I first thought about getting my eyes done, I refused to go to the regularly advertised companies as I found them too pushy and unsatisfactory when it came to answering my questions. However, when visiting Ms Saw she immediately put me at ease. My concerns over side effects and dry eyes were put to one side once Ms Saw explained very clearly and in detail what the likely outcome would be and how I would be able to look after my dry eyes. Ms Saw advised me to use a hot compress which worked very well in preparation for the procedure and I continue to use this method. It’s now been two years since I've had the operation and I've got to say I've had minimal pain and discomfort. It's now two years on and despite dry eyes and fear of side effects, I could not be happier with the outcome. My vision is fantastic and it feels wonderful to be able to wake up, watch tv, go for a walk or even look at signs on the tube platforms without using my glasses. Ms Saw's care pre and post operation have been exceptional. If you are in any way apprehensive or nervous, I highly recommend Ms Saw. Quite simply you could not be in better hands!

    Ms Dhaliwal

  • Ms Saw and her staff were outstanding and very helpful. Treatment and post-care were easy. I would highly recommend her and this clinic to anyone considering the procedure. Well worth it

    TCK

  • Ms Valerie Saw’s team were very attentive and helpful. I had LASEK surgery which has longer recovery time and is more painful. Ms Saw ensured the pain has kept to a minimum and even came in on a Saturday to check how my eyes were healing! All my questions were answered promptly.

    Jabin Ahmed

  • I can’t thank Valerie enough for completely transforming my vision: from -8.50 and virtually no vision without glasses or lenses to perfect vision for both distance and reading. At all stages Valerie provided a totally professional service. The aftercare support was fantastic. I cannot think of a more successful outcome nor a surgeon I could more highly recommend.

    Timothy Oliver

  • After being blind as a bat for over 30 years, I finally gave into having laser eye surgery. After researching the issue, I decided on Moorfields as the best option. This has been endorsed by my whole experience from start to finish. Miss Saw and her team were professional, dedicated and supportive through the whole process and I wouldn’t hesitate to recommend them as the way to go if you're thinking of this treatment. Thanks for giving me my sight back!

    Andrew Rowley

  • I could not be happier with my decision to have laser eye surgery to correct short-sightedness/ astigmatism performed by Miss Saw. Miss Saw is professional, calm and reassuring. She talked me through the procedure which took around 10-15 minutes one afternoon. I woke up the next morning and could see without glasses or lenses for the first time in 30 years. A year on I have 20/20 vision, no problems driving at night or otherwise. Brilliant!

    Julie Brownson

  • I found Valerie very informative prior to having my eye implants, the aftercare was first class. I would not hesitate to recommend Valerie to any of my friends who were thinking of having this procedure.

    Pamela Weeks

  • Having worn glasses since the age of 8, it was difficult to explain the decision to undergo surgery to correct my vision. However, how glad I am that I went through with it. Valerie was amazing, patiently explaining everything and answering questions, even in the run-up to the surgery date. On the day itself, Valerie and her team made the whole experience calm and stress free and it is astounding that such a life changing result can be achieved so easily, and pain/ stress free. I had the surgery in February and have recently returned from an early summer holiday – no glasses, prescription sunglasses, contact lenses, comfort drops etc. Just my new eyes and a pair of sunglasses! I would thoroughly recommend the amazing Valerie and Moorfields hospital.

    Tony Millward

  • Valerie was highly professional and very competent indeed and the Lasik surgery on my left eye went really well. The procedure was explained very clearly in advance and the procedure itself was quick and painless and has resulted in clear long distance vision in the eye. It all went very well and I can strongly recommend Valerie.

    Michael Hart

  • What a lovely lady! What a fantastic surgeon. My husband has only had one good eye since birth, and that was getting worse and worse. He had to wear glasses all the time and it makes things like wearing goggles for skiing and workshop tasks difficult. He went to a couple of laser surgeons to find out if he could have something done to this one eye, but, they wouldn't even consider it in case something went wrong. However, we went to see Miss Saw and she didn't see any problems, she only saw solutions. He now has 20/20 vision in that eye and sees better than he has since his 20's. It was easy, friendly and a comfortable experience for both of us. Can't praise her enough. Wonderful, she has changed his life.

    Carole Jones

  • The surgery itself was quick and (literally) painless. I am 3 months down the line and delighted, not only with the result but with the follow up care I received. I highly recommend Valerie and her whole team. I could not have done this without them!

    Verity Westcott

  • After years of suffering with dry eyes and several visits to consultants in the Midlands, I was getting extremely frustrated and losing hope of finding anyone who could understand my problem fully and offer me sound advice with a plan for improvement. I had both Meibomian gland dysfunction and aqueous tear deficiency, with occasional secondary inflammation. Since 2002 I had used a variety of drops and also tried punctal plugs, but had developed infections.

    After another search on the Internet and looking at London consultants, I noticed Ms Saw had an amazing CV and had Dry Eye as one of her areas of expertise. My first visit to Valerie in March 2015, instantly gave me the hope I was seeking. She was so understanding, reassuring and kind. Valerie took time to investigate and diagnose my symptoms fully and I came away with a new treatment regime offering various options, as part of a plan for improving my condition in the short and long term. As one of my treatment options, Valerie carried out Cautery of the lower tear ducts and fitting of a punctual plug in one of the upper.

    In 2016 my eyes are now far more comfortable and I am slowly reducing medication. I am using a good combination of drops and ointment and continue with a hot massage routine.
    I have travelled from Staffordshire for all of my visits and will happily continue to do so, Valerie is unique in my view, and so it is well worth the effort to get the best.

    Clearly our rating out of 5 is 6

    Mrs Stephanie James

  • Very pleased with the results. The novelty has not worn off yet! Ms Saw is very gentle and calm. I would do it all again in a heartbeat.

    Charlotte Leonard

  • As most people would be when thinking about having eye surgery, I was really worried about side effects. however, Ms Saw put all my worries to rest while at the same time being very informative and professional. My visits to the clinic were enjoyable and the people who worked there were really friendly. I had a great outcome with my surgery and would recommend Ms Saw to anybody

    Mark Glock

  • After 40+ years of glasses/contacts had LASIK about three months ago. Miss Saw and her team were excellent. Friendly, professional and thorough. I understood all aspects of the procedure and could not be happier with the results.

    Mrs N

  • The initial examination was thorough beyond all previous experience and her advice complete, informative and very reassuring. Taking the plunge I elected to have lasik surgery and the procedure was duly completed without pain in a calm and comforting environment by a scrupulously professional team led by Valerie. Despite the recent surgery there was an immediate and staggering improvement in my vision and within 12 hours I could read newsprint without the aid spectacles. It is now 4 months since the procedure and having undergone 3 equally thorough post operative checks the result continues to improve. I am now free to pursue my passion for wildlife photography and bird watching without the constant annoyance of spectacles hanging around my neck and the only regret is that I didn't have the procedure carried out years ago! If you are in any doubt forget it, make an appointment to see Valerie, put your trust in her abilities and enjoy a life changing experience. Brilliant!

    Nick Stantiford

  • Had my surgery over a year ago. Currently still no issues and have better than 6/6 or 20/20 vision. Miss Saw was very thorough and that gave me the confidence to go ahead with the surgery. She also explained that if I had any issues after surgery to contact her immediately. That alone gave me confidence I was in good hands. The surgery was quicker than I expected. Before long I suddenly could see with a lot of detail. Also to note Miss Saw is very gentle as well. Best thing I have ever done and better still with such an excellent surgeon.

    Sarah Datson

  • From start to finish service spot on, Professional, informative and end result
    amazing!! I wouldn’t hesitate recommending Ms Valerie Saw and team to Family friends and colleagues.

    Andrew Lee

  • I am extremely glad I went with Valerie and her team, they were friendly, caring, informative and professional. The surgery was so quick, easy and pain free. I was extremely nervous about the procedure, just the thought made my stomach turn. Valerie and her team made me feel extremely relaxed and explained the procedure clearly to me. The nurses on the day were really helpful and explained all the aftercare drops to me. I still can’t believe I went through with it but so glad I did and would recommend it to anyone and would highly recommend going to Moorfields and having Valerie as your surgeon. Her voice is extremely calming whilst the procedure is taking place.

    Sarah Dean

  • I was so afraid of this operation but Ms Saw has a calm and gentle manner which is so reassuring to the patient. Her skills are outstanding – I can’t remember being able to see from early childhood, but because of Ms Saw’s abilities a miracle has occurred and I can see when I open my eyes. I am so grateful to her.

    Brenda Garnham

  • Very satisfied with my treatment. Ms Saw is excellent and the quality of aftercare is fantastic. I would highly recommend treatment here and I am delighted with the results.

    David Sindall

  • Extremely pleased with the surgery (January 2016). It is life changing. Valerie was fantastic all the way through, very professional and thorough in her explanations. Surgery was painless and results were already incredible after a few hours. After care support was brilliant. I have been recommending Valerie to my family and friends since then!

    Leonardo L.

  • The service provided by Valerie and her team was fantastic and I am very pleased with the results. I would not hesitate to recommend her to any of my friends or family.

    Caolan Gardner

  • I had spent a lot of time researching LASIK surgery as it was something that I was fearful of having done, even though I really wanted to improve my sight. I could not have chosen a better surgeon than Valerie Saw. Not only did she keep me fully reassured and informed at all time, her manner and personality left me feeling instantly at ease in her care. The treatment itself was not as scary as I had anticipated and either Valerie or her team were always at the other end of the phone if I needed assistance with aftercare. It has been one of the best decisions I have made and I am so pleased that I chose Valerie for my treatment.

    Richard Knight

  • I went to a number of eye clinics who all failed to spot my cataracts. Valerie was quick to diagnose and treat my various needs and swiftly achieved great results. If you are worried or in need of advice or quality care I would recommend Valerie.

    Nicholas Pollitt

  • Dr Saw completed my laser eye surgery in November 2016. Her team completed a thorough pre-assessment of my eyes and determined I was suitable for surgery. On the day of the surgery I was walked through the process step-by-step to ensure I was comfortable with what was going to happen, as well as information about how long different things would take.
    I’ve had several follow up appointments and have reached out to Dr Saw multiple times with questions, all of which have been responded to promptly. My vision is now better than 20/20.
    
My wife is also looking to get laser eye surgery and we'll definitely be going back to see Dr Saw!

    Graham R.

  • I had a corneal ulcer on my right eye caused by my contact lenses. I was under her care for 3 months whilst the ulcer healed. I received excellent care and so I decided to go back to Ms Saw to discuss the possibility of laser surgery. The final procedure was completely successful. I can now say, June 2014 that I have 20:20 vision in both eyes. It is amazing and I am SO grateful to Ms Saw for her professionalism and care. Despite being an ‘unusual’ case, she was willing to treat me and I hope that my experience will give hope to others in a similar situation. I have no hesitation in recommending Ms Saw and would highly recommend her.

    Pippa Berger

  • After many years debating whether to have surgery I eventually booked an appointment with Ms Saw. Valerie and her team explained everything fully, addressed my worries and put me at ease. The procedure was easier than I thought it would be and I only wish I had done it sooner. Thanks to Ms Saw I do not need glasses anymore.

    Lynda Parker

  • Having a very high prescription most of my life was restricting in everyday life. I waited until I was ready to take the plunge and have the eye surgery (mainly due to confidence and checking to see what would be suitable for my high prescription). Ms Saw has been very helpful and supportive during the whole procedure and we have both been surprised and happy by the results of the surgery

    Deepkamal Bakhshi

  • Great level of care. I felt that they really cared at all stages through the consultancy all the way to the surgery and then the aftercare. I was able to call anytime if I had a problem. Perfect vision. I would highly recommend it to anyone considering laser eye surgery.

    Taharul Islam

  • Absolutely delighted with result and service, couldn't be happier!

    Heather Pearce

  • As I got older my eyes deteriorated! I had glasses throughout the house, and it irritated me. It even influenced my sports. This operation has given me perfect vision, I could not be happier! Thank you Ms Valerie Saw and the team for the perfect treatment. Highly recommended.

    Yvette Van Leeuwen

  • I highly recommend undertaking laser surgery with Valerie. I had a very high prescription (-8) and was wearing spectacles and then contact lenses since I was 5 years old. I was a bit apprehensive at the start but Valerie was very reassuring from the beginning. I received all the information I wanted allowing me to make my choice. The surgery (in May 2016) didn’t take long at all and the discomfort only lasted a couple of hours. I was provided with a range of drops including anesthetics drops against the pain which were very efficient. After a few hours, I was seeing and my vision settled very quickly after then. I was driving my son to school after 48h. Valerie gave me her mobile number allowing me to call her, anytime (even during the weekend) if I had any concerns. This was really reassuring. She is making herself available for her patients and is very caring. My vision is now perfect, which is an amazing and crazy feeling! Whenever friends mention laser surgery, I encourage them to see Valerie as I know they will be in very safe hands. The clinic facilities at AVC are very clean and modern, as you would expect for private facilities. You are very well looked after all way through.

    Lauren A.

  • Ms Saw is excellent. She is so reassuring about the procedure, explaining good and bad about the surgery. I would strongly recommend her to anyone considering surgery.

    Diane McGarva

  • The treatment was completely successful. Great to be able to drive without glasses and to buy sunglasses without having to get expensive lenses. Wish I’d done it sooner, best money I’ve ever spent!

    Niroshini Gallacher

  • I wish I’d had the treatment years ago. It’s transformed my life, stripping out a whole layer of stress, anxiety and upset. I was terrified of the procedure and the recovery process for PRK. It was over in moments and in retrospect, neither the treatment or recovery felt like a big deal. I can’t recommend Valerie Saw highly enough. She took time to answer my numerous questions in-depth, face-to-face during consultations as well as over the phone and via email. She put me at ease and she has changed my life for the better, and for this I am eternally grateful.

    Alex Smith

  • I have always considered having laser eye surgery. After using contact lenses and glasses for over 10 years, I decided to go ahead with it. After going online to look at reviews on Moorfields website Ms V Saw had very good feedback. Having had a consultation which was brilliant and answered all my questions, I then decided to proceed with surgery. Obviously going in for the surgery can seem quite daunting but everyone, especially Miss Saw, put me at ease and told me what was happening throughout the procedure. It has been the best thing I have ever done and would do it all over again! Miss Saw was fantastic. I would recommend her to anyone considering Lasik Surgery. Thank you!

    Elizabeth Godfrey

  • I was considering having laser eye surgery on my right eye. I consulted Valerie who diagnosed me with keratoconus. Valerie recommended inserting a Keraring in my eye instead of laser treatment. The results are amazing, 20/20 vision achieved. I cannot thank Valerie enough.

    Kevin Carnegie

  • While I was initially quite frightened and apprehensive considering eye surgery to correct my short sightedness, I opted to go to Valerie Saw at Moorfields due to the consistency of references I had received about her. This was absolutely the right decision. She worked carefully with me, addressing all my concerns and answering my questions, no matter how unusual! In the end we planned a surgery type that was right for me, and I felt confident on the day that I was being looked after as well as I had ever hoped. Valerie comforted me massively during the surgery, and offered me all sorts of advice and post surgery care as I recovered. I highly recommend her to anyone, and I am very grateful.

    Matt De Moraes

  • Brilliant Service. Everyone was kind and helpful. Can now see my golf ball after playing my shot. Highly recommended.

    David Pollicott

  • I had lens replacement (IOL, RLE) surgery to fix short-sightedness in Feb/Mar 2013. I’ve had my first annual check up everything is fine. I’m extremely happy with the outcome and would happily recommend this surgery to anyone, especially if you have severe short-sightedness. Valerie Saw is not only highly qualified, but helpful, kind, gentle and patient as well and I highly recommend her to anyone considering this type of surgery.

    Louise De Kock

  • I had LASIK after suffering from iritis and blepharitis. I was very nervous about the procedure but Ms Saw was very clear in explaining what would happen, which made me feel at ease on the day. My LASIK result was overwhelming with joy that such instant results could change my sight from -6.5 to 20/20. Thank you!

    Elizabeth Selvey

  • Having laser eye surgery was the best decision I have ever made and, given the serious nature of the surgery, I researched the procedure and the best surgeon for me before committing to it. The whole experience was excellent - professional, caring and I was kept completely informed throughout the process.

    Katie Price

  • Extremely pleased with the results from my laser eye surgery with Ms Saw. Perfect vision, better than 20:20. Still marvelling at the view 4 months on. Ms Saw and her team are kind, thorough, professional and provide excellent care and advice. Highly recommend.

    Justin Wilson

  • Ms Saw and her team are very friendly and professional – they made sure I understood everything beforehand and explained exactly how the procedure would go so I knew what to expect. Ms Saw’s manner is calm and reassuring and I am thrilled with the results.

    Kit Roberts

  • By the end of the first consultation, I felt sure I knew what I was entering into. During the surgery, Ms Saw explained the progress the laser was making, and kept me calm. I would highly recommend having the surgery with Valerie Saw, who is calm in speech and professional in approach, essential qualities when dealing with patients looking to make important decisions on issues as sensitive as their sight.

    Aatish Thakerar

  • Lens replacement surgery in November 2016.
    Not needing reading glasses is amazing!

    Rick B.

  • Valerie Saw carried out cataract surgery on me as a private patient in April of 2011 at Moorfields Eye Hospital in London. I am absolutely delighted with the outcome and can't praise her skills enough.

    Kenneth Fish
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London Dry Eye Clinic